Genetics Review Questions

Review Questions made by the Year 10's

Ya'll fantastic.

Draw a double helix and label it.	What are the nitrogen bases?	What is DNA made up of?	What is phenotypic plasticity?
What does semi – conservative mean?	What is DNA replication?	DNA replication begins with?	What is a genotype?
What is a phenotype?	What is the phenotype influenced by?	What plays a major role in your genetics?	What is mutation?
What is an example of a good type of mutation?	What is an example of a bad type of mutation?	What are genes made up of?	What is the relationship between DNA and protein?
Describe the steps for protein synthesis.	What is a gene?	What is an allele?	Write an example of a dominant allele and recessive allele.
If you are born in a hot area are you more resistant to heat or less resistant?	What is DNA responsible for? What shape is DNA?	What part of DNA is responsible for the inheritance of characteristics?	What four nucleotide bases bind to make DNA?
What is a karyotype?	What is the function of a karyotype?	What does a human karyotype look like? Draw an example.	Explain how the gender of a baby is determined.
What are the female and male sex gametes called?	What are the sex chromosomes that males and females have?	Complete the Punnett Square with the parents’ sex chromosomes.	What is the probability of obtaining a male or female child?
What is a mutagen?	What are some other environmental factors that can cause mutations?	When cells undergo mitosis, new cells contain the same number of chromosomes as the original cell. True / False?	When cells undergo meiosis, do new cells have the same chromosomal number as the original cell?
When mitosis occurs, how many new cells are created? (1, 2, or 3).	What is heterozygous?	What is homozygous?	Explain what a recessive trait is. What happens when you have a recessive trait?

Words for your concept map

Letter to the Doctor

For those who are yet to complete their letter due to Drivers Ed,  instructions are listed here: 

http://teachme-teachyou.blogspot.com.au/2015/09/lesson-3-gene-therapy.html

Instead of writing 350 - 400 words, you will write 300 words. 

Submission Requirements

Please submit the letter either printed out, emailed or on a USB on Wednesday 16th September.

An excellent student example of a letter to the doctor:

Success criteria

1. A description of the disease. ✓
2. The symptoms you have been experiencing at any stage of diagnosis. ✓
3. How it is caused. ✓
4. The current research on gene therapy for your disease. ✓
5. Risks and issues with the procedure. ✓
6. Alternative treatments. ✓
7. Final statement whether you would or wouldn't seek gene therapy.  ✓

...

Dear Dr Smith,

I’m a student studying science and I have recently been diagnosed with muscular dystrophy which is a genetic disorder that causes progressive weakness and degeneration of the muscles that help the body move. Muscular dystrophy can occur at any age and those who are affected gradually lose the ability to do things such as walking and sitting upright, each disorder has different degrees of carer and mobility needs and independence. There are 30 different types of muscular dystrophy and some are further divided into sub-types. I’m currently awaiting blood test results with the specific type of disorder that I have.

I have done some research and found out that some symptoms of muscular dystrophy include a waddling walk, well-developed or excessively large calf muscles with other muscles poorly developed or a sway back (lordosis). I personally have a tendency to stand and walk on the forefoot, with the heel off the ground and suffer from frequent falls and difficulty rising up from the ground or going up hills or stairs.

Muscular dystrophy is caused when people such as I, have incorrect or missing information in their genes, this prevents us from making proteins that are needed for healthy muscles. The disorder can be diagnosed through genetic testing, a blood test; which will show very high levels of protein called creatine phosphokinaseand which is how I found out about my disorder, a muscle biopsy; the removal of a small piece of muscle tissue that is then examined under a microscope or electromyography; insertion of a thin needle that checks the health of the muscles and the nerves that control the muscles.

I have been told that there is currently no cure for muscular dystrophy but several possible treatments are beginning to emerge and are in clinical trial because of medical researches building a greater understanding of MD. However, the discovery of a cure for one type of muscular dystrophy may not necessarily help in curing another type.

Identifying the right form of a gene to deliver is the most current research that gene therapy is focused on in MD, as well as developing methods for safe and efficient delivery to muscle. According to other doctors the task is not easy to perform due to many of the genes being huge and they present complex expression patterns. For a successful delivery it must overcome immunological and physical barriers, but I am willing to undergo this method. 

I have been told that although there is currently no cure for muscular dystrophy, there are alternative treatments to help relieve symptoms of the disorder such as exercise and physical therapy to minimize abnormal or painful positioning of the joints as well as respiratory care, coughing and deep breathing exercises. Surgery can also sometimes relieve muscle shortening and canes, powered wheelchairs and other rehabilitative devices can help those with MD maintain mobility and independence.

I am writing to you because I would like to have genetic therapy as I am feeling a lot of pain and physical therapy isn’t doing the job for me. I want to undergo this kind of treatment because there is a chance of a positive outcome.

Kind regards,

B.C

Lesson 3: Gene therapy

Key skills

• Discuss gene therapy techniques and evaluate the risks involved when treating a disease. 

Homework task

• Begin researching the disease you have by using the internet or information books. 
• You are to provide a written formal letter of consent for gene therapy to your doctor. 

Your letter of consent must include (350 - 400 words):

1. A description of the disease. 
2. The symptoms you have been experiencing at any stage of diagnosis. 
3. How it is caused. 
4. The current research on gene therapy for your disease. 
5. Risks and issues with the procedure. 
6. Alternative treatments. 
7. Final statement whether you would or wouldn't seek gene therapy.  

We will be in the library on Wednesday 9th September. You must complete your research in the period and submit your letter here where it will be posted onto the blog. Make sure you complete your questions for homework as well! We will be going through the answers on Wednesday. 
See you next week. 

Lesson Resources

PPT

Lesson 2 - Cloning: The Good and the Ugly.

You and I are one of a kind? But what if you're not? What if we could make a duplicate of you?

Key Knowledge

• Evaluate the advantages and disadvantages of gene cloning. 
• Consider the moral issues with human cloning. 

The Case of Dolly the Sheep

Homework task

Question 13 (p. 62)

• Look at Science Daily and select one article under "Related Stories". 
• Design a flow chart outlining the process they used to clone. 
• Discuss the disadvantages and advantages of gene cloning stated in the article. 
• What can you conclude after reading this article? 

Lesson Resources

PPT

Lesson 1 - Changing the Code

37 Animals with the most unique colour mutations

Key Knowledge

• Describing mutations as changes in DNA or chromosomes and outlining the factors that contribute to causing mutations (ACSSU184). 

 

What happens when there's an error in the message?

It was great to meet you all this lesson! You guys were fantastic with each activity. We'll be looking at cloning tomorrow. Don't forget to finish the questions from today's lesson: 

Homework task due Friday 4th September

Question 1 - 12 (pg. 45) 

Lesson Resources

Changing the code PPT slides

Lab interactive mutations (Online activity)

...

Any questions? 

studentteacherkaren@gmail.com